Application
Immunohistochemistry staining of PDE9A in spleen tissue using PDE9A Antibody.| Product Name | PDE9A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PDE9A, Pde9A1, Pde9a2, Pde9a3, Pde9a4, Phosphodiesterase 9A, Phosphodiesterase PDE9A21, HSPDE9A2 |
| Product description | Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling. |
| Immunogen | PDE9A antibody was raised against a peptide located near the internal domain of PDE9A (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| PDE9A antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
|
| Species Reactivity | DogGibbonHumanMonkey |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PDE9A |
|---|---|
| Alternative Names | PDE9A Pde9A1 Pde9a2 Pde9a3 Pde9a4 Phosphodiesterase 9A Phosphodiesterase PDE9A21 HSPDE9A2 |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Application
Immunohistochemistry staining of PDE9A in spleen tissue using PDE9A Antibody.| Application Notes | PDE9A antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | PDE9A antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
