Application
Western blot analysis of PDGF-B in rat liver tissue lysate with PDGF-B antibody at (A) 1 and (B) 2 μg/mL.Application
Immunofluorescence of PDGF-B in human liver tissue with PDGF-B antibody at 20 μg/ml.| Product Name | PDGF-B Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PDGF-B Antibody: SIS, SSV, IBGC5, PDGF2, c-sis, PDGF-2, SIS, Platelet-derived growth factor subunit B, PDGF subunit B |
| Product description | PDGF-B Antibody: The platelet-derived growth factor beta (PDGF-B) is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB). Mutations in this gene are associated with meningioma , and reciprocal translocations between chromosomes 22 and 7, at sites where the PDGF-B gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans.1) Johnsson A, Heldin CH, Wasteson A, et al. The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor. EMBO J. 1984; 3:921-8. |
| Immunogen | Rabbit polyclonal PDGF-B antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PDGF-B. The immunogen is located within the last 50 amino acids of PDGF-B. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFWB |
| PDGF-B antibody can be used for detection of PDGF-B by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PDGFB |
|---|---|
| Alternative Names | PDGF-B Antibody: SIS SSV IBGC5 PDGF2 c-sis PDGF-2 SIS Platelet-derived growth factor subunit B PDGF subunit B |
| Molecular Weight(MW) | Predicted: 27 kDa |
| Sequence Similarities | 2) Cat. No. 10-201 - Human Liver Tissue Slide |
Application
Western blot analysis of PDGF-B in rat liver tissue lysate with PDGF-B antibody at (A) 1 and (B) 2 μg/mL.
Application
Immunofluorescence of PDGF-B in human liver tissue with PDGF-B antibody at 20 μg/ml.| Positive Control | 1) Cat. No. 1464 - Rat Liver Tissue Lysate |
|---|---|
| Application Notes | PDGF-B antibody can be used for detection of PDGF-B by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | PDGF-B antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | PDGF-B Antibody is supplied in PBS containing 0.02% sodium azide. |
