Application
Immunohistochemistry staining of PDGFRA in skin tissue using PDGFRA Antibody.| Product Name | PDGFRA Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PDGFRA, CD140A, CD140a antigen, PDGFalphaR, PDGFR2, PDGFRalpha, AlphaPDGFR, RHEPDGFRA, PDGF receptor alpha, PDGFR-2, PDGFRA/BCR fusion, APDGFR, Pdgf alpha-receptor, PDGF-R-alpha, PDGFR-alpha |
| Product description | Platelet-derived Growth Factor Receptor Alpha (PDGFR alpha), a member of the a PDGF Receptor tyrosine kinase family, is a mediator of the biological actions of platelet-derived growth factor (PDGF). PDGF binding to PDGF receptors result in stimulation of cell growth, chemotaxis, and cell shape changes. Unlike PDGFR beta, PDGFR alpha can bind to both PDGF subunits. PDGFR alpha has been implicated in the development of spina bifida. In various mouse models, deregulated PDGFR alpha expression was found to result in congenital neural tube defects. In humans, various PDGFRA promoter haplotypes have been associated with neural tube defects. |
| Immunogen | Amino acids 1063 to 1077 of human PDGFRA |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC |
| PDGFRA antibody can be used in ELISA, and immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | PDGFRA |
|---|---|
| Alternative Names | PDGFRA CD140A CD140a antigen PDGFalphaR PDGFR2 PDGFRalpha AlphaPDGFR RHEPDGFRA PDGF receptor alpha PDGFR-2 PDGFRA/BCR fusion APDGFR Pdgf alpha-receptor PDGF-R-alpha PDGFR-alpha |
Application
Immunohistochemistry staining of PDGFRA in skin tissue using PDGFRA Antibody.| Application Notes | PDGFRA antibody can be used in ELISA, and immunohistochemistry starting at 5 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | PDGFRA antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
