This gene encodes a protein that is abnormally elevated in
malignant tumors of astrocytic origin. It is a strongly conserved
gene containing a BRCT domain that is essential for the activity of
this gene product. The gene plays a crucial role in cell
proliferation and may be necessary for oncogenic transformation and
tumor progression.1) Zhang, J., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(12):991-997(2009)
Immunogen
This PES1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-578 amino acids from the C-terminal region of human PES1.
Western blot analysis in U251 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.