This gene encodes a member of the AAA ATPase family, a
large group of ATPases associated with diverse cellular activities.
This protein is cytoplasmic but is often anchored to a peroxisomal
membrane where it forms a heteromeric complex and plays a role in
the import of proteins into peroxisomes and peroxisome biogenesis.
Mutations in this gene have been associated with complementation
group 1 peroxisomal disorders such as neonatal
adrenoleukodystrophy, infantile Refsum disease, and Zellweger
syndrome.1) Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Immunogen
This PEX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 599-628 amino acids from the Central region of human PEX1.
Western blot analysis in MCF-7 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.