This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.1) Cloutier, P., et al. Methods 48(4):381-386(2009) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)Simons, C.T., et al. J. Biol. Chem. 279(6):4196-4203(2004) Bouwmeester, T., et al. Nat. Cell Biol. 6(2):97-105(2004) Hu, R.M., et al. Proc. Natl. Acad. Sci. U.S.A. 97(17):9543-9548(2000)
Immunogen
This PFDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-125 amino acids from the C-terminal region of human PFDN2.
Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.