Application
Western blot analysis of PGCC1 in rat thymus tissue lysate with PGCC1 antibody at (A) 0.5 and (B) 1 μg/mL.| Product Name | PGCC1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PGCC1 Antibody: CCPG, PGCC1, KIAA1838, dJ894D12.1, CCPG, Constitutive coactivator of peroxisome proliferator-activated receptor gamma, PPARG constitutive coactivator 1, Constitutive coactivator of PPAR-gamma |
| Product description | PGCC1 Antibody: The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist.1) Berger J and Moller DE. The mechanisms of actions of PPARs. Annu. Rev. Med.2002; 53:409-35. |
| Immunogen | PGCC1 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human PGCC1. The immunogen is located within the last 50 amino acids of PGCC1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| PGCC1 antibody can be used for detection of PGCC1 by Western blot at 0.5 - 1 μg/mL.: |
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| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FAM120B |
|---|---|
| Alternative Names | PGCC1 Antibody: CCPG PGCC1 KIAA1838 dJ894D12.1 CCPG Constitutive coactivator of peroxisome proliferator-activated receptor gamma PPARG constitutive coactivator 1 Constitutive coactivator of PPAR-gamma |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine: (92%) |
| Tissue Specificity | This antibody will not cross-react with FAM120A. |
Application
Western blot analysis of PGCC1 in rat thymus tissue lysate with PGCC1 antibody at (A) 0.5 and (B) 1 μg/mL.| Positive Control | 1) Cat. No. 1471 - Rat Thymus Tissue Lysate |
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| Application Notes | PGCC1 antibody can be used for detection of PGCC1 by Western blot at 0.5 - 1 μg/mL.: |
| Form | Liquid |
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| Storage Instructions | PGCC1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | PGCC1 Antibody is supplied in PBS containing 0.02% sodium azide. |
