Application
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.| Product Name | PHB2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PHB2, BAP, BCAP37, Bap37, MGC117268, PNAS-141, REA, p22 |
| Product description | PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.1) Ross, J.A., (2008) J. Biol. Chem. 283 (8), 4699-4713. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PHB2. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| PHB2 antibody can be used for detection of PHB2 by ELISA at 1:62500. PHB2 antibody can be used for detection of PHB2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PHB2 |
|---|---|
| Alternative Names | PHB2 BAP BCAP37 Bap37 MGC117268 PNAS-141 REA p22 |
| Molecular Weight(MW) | 33 kDa |
Application
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | PHB2 antibody can be used for detection of PHB2 by ELISA at 1:62500. PHB2 antibody can be used for detection of PHB2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store PHB2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
