Application
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with PI3KC2B antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.| Product Name | PI3KC2B Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, PI3K-C2-beta, PtdIns-3-kinase C2 subunit beta, C2-PI3K, Phosphoinositide 3-kinase-C2-beta, PIK3C2B |
| Product description | Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.1) Arcaro, A., et al., J. Biol. Chem. 273(49):33082-33090 (1998). |
| Immunogen | This PI3KC2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-150 amino acids from the N-terminal region of human PI3KC2B. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | PIK3C2B |
|---|---|
| Alternative Names | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta PI3K-C2-beta PtdIns-3-kinase C2 subunit beta C2-PI3K Phosphoinositide 3-kinase-C2-beta PIK3C2B |
| Molecular Weight(MW) | 185 kDa |
Application
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with PI3KC2B antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.| Application Notes | For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
