Application
Immunohistochemistry of PBIF in spleen tissue with PBIF antibody at 5 μg/ml.Application
Immunofluorescence of PBIF in human spleen tissue with PBIF antibody at 20 μg/ml.Application
Western blot analysis of PIBF1 in human placenta tissue lysate with PIBF1 antibody at (A) 1 and (B) 2 μg/mL| Product Name | PIBF1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PIBF1 Antibody: PIBF, CEP90, C13orf24, PIBF, Progesterone-induced-blocking factor 1 |
| Product description | PIBF1 Antibody: PIBF1 is synthesized during pregnancy in response to progesterone by T lymphocytes. PIBF1 inhibits arachidonic acid release, controls NK activity, and modifies the cytokine balance exerting an anti-abortive effect. It contains a leucine zipper motif, a basic zipper sequence, a PEST sequence, a nuclear localization signal, an ER membrane retention signal and N-glycosylation and phosphorylation sites. PIBF1 is significantly higher in healthy pregnant women than in women at risk for premature pregnancy termination. Full-length PIBF1 is associated with the nucleus and functions as a transcription factor, whereas secretion of shorter forms which may act as cytokines is induced by activation of the cell.1) Laskarin G, Tokmadzic VS, Strbo N, et al. Progesterone induced blocking factor (PIBF) mediates progesterone induced suppression of decidual lymphocyte cytotoxicity. Am. J. Reprod. Immunol. 2002; 48:201-9. |
| Immunogen | Rabbit polyclonal PIBF1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human PIBF1. The immunogen is located within amino acids 610 - 660 of PIBF1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| PIBF1 antibody can be used for detection of PIBF1 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PIBF1 |
|---|---|
| Alternative Names | PIBF1 Antibody: PIBF CEP90 C13orf24 PIBF Progesterone-induced-blocking factor 1 |
| Molecular Weight(MW) | 83 kDa |
| Sequence Similarities | 2) Cat. No. 10-901 - Human Spleen Tissue Slide |
| Tissue Specificity | Multiple isoforms of PIBF1 exists as a result of alternative splicing event. |
Application
Immunohistochemistry of PBIF in spleen tissue with PBIF antibody at 5 μg/ml.
Application
Immunofluorescence of PBIF in human spleen tissue with PBIF antibody at 20 μg/ml.
Application
Western blot analysis of PIBF1 in human placenta tissue lysate with PIBF1 antibody at (A) 1 and (B) 2 μg/mL| Positive Control | 1) Cat. No. 1309 - Human Placenta Tissue Lysate |
|---|---|
| Application Notes | PIBF1 antibody can be used for detection of PIBF1 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | PIBF1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | PIBF1 Antibody is supplied in PBS containing 0.02% sodium azide. |
