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PKP2 Antibody

Catalog Number:OM288233
OM288233
Discount Price
OM288233-100ul
1~2 Week
100ul
OM288233-50ul
50ul
OM288233-20ul
20ul
1~2 Week
Product Profile
Product Name PKP2 Antibody
Antibody Type Primary Antibodies
Antigen Alias Plakophilin-2, PKP2
Product description This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.1) Fressart, V., et al. Europace 12(6):861-868(2010)
Immunogen This PKP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 838-866 amino acids from the C-terminal region of human PKP2.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol PKP2
Alternative Names Plakophilin-2
PKP2
Molecular Weight(MW) 97 kDa
Database Links
Entrez Gene 5318
Protein Accession Q99959
Application

Application

PKP2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Application

Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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