Group 3 secretory phospholipase A2, Group III secretory phospholipase A2, GIII sPLA2, sPLA2-III, Phosphatidylcholine 2-acylhydrolase 3, PLA2G3
Product description
PLA2G3 belongs to the family of secreted phospholipase A2 (sPLA2; EC 3.1.1.4) proteins. These Ca(2+)-dependent lipolytic enzymes have a conserved Ca(2+)-binding loop and a his-asp dyad in the catalytic site (Murakami et al., 2003 [PubMed 12522102]).1) Wang, G., et al. J. Neurochem. 114(4):1039-1048(2010) Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010) Segat, L., et al. Vaccine 28(10):2201-2206(2010) Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010) Sato, H., et al. Biochem. J. 421(1):17-27(2009)
Immunogen
This PLA2G3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-474 amino acids from the C-terminal region of human PLA2G3.
Western blot analysis in Uterus tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.