Application
Immunofluorescence of PLAC1 in Hela cells with PLAC1 antibody at 20 μg/mL.Application
Immunocytochemistry of PLAC1 in HeLa cells with PLAC1 antibody at 10 μg/mL.Application
Western blot analysis of PLAC1 in human placenta tissue lysate with PLAC1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Product Name | PLAC1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PLAC1 Antibody: CT92, OOSP2L, Placenta-specific protein 1 |
| Product description | PLAC1 Antibody: PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.1) Cocchia M, Humber R, Pantano S, et al. PLAC1, an Xq26 gene with placenta-specific expression. Genomics2000; 68:305-12. |
| Immunogen | PLAC1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human PLAC1. The immunogen is located within amino acids 130 - 180 of PLAC1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICCIFWB |
| PLAC1 antibody can be used for detection of PLAC1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PLAC1 |
|---|---|
| Alternative Names | PLAC1 Antibody: CT92 OOSP2L Placenta-specific protein 1 |
| Sequence Similarities | 2) Cat. No. 17-001 - HeLa Cell Slide |
Application
Immunofluorescence of PLAC1 in Hela cells with PLAC1 antibody at 20 μg/mL.
Application
Immunocytochemistry of PLAC1 in HeLa cells with PLAC1 antibody at 10 μg/mL.
Application
Western blot analysis of PLAC1 in human placenta tissue lysate with PLAC1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Positive Control | 1) Cat. No. 1309 - Human Placenta Tissue Lysate |
|---|---|
| Application Notes | PLAC1 antibody can be used for detection of PLAC1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | PLAC1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | PLAC1 Antibody is supplied in PBS containing 0.02% sodium azide. |
