Application
Immunofluorescence of PLAGL2 in rat brain tissue with PLAGL2 antibody at 20 μg/ml.Application
Immunohistochemistry of PLAGL2 in rat brain tissue with PLAGL2 antibody at 2 μg/ml.Application
Western blot analysis of PLAGL2 in rat brain tissue lysate with PLAGL2 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | PLAGL2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PLAGL2 Antibody: ZNF900, KIAA0198, Zinc finger protein PLAGL2, Pleiomorphic adenoma-like protein 2 |
| Product description | PLAGL2 Antibody: The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins include PLAG1, ZAC1 and PLAG-like 2 (PLAGL2). PLAG1 is the target gene for the pleiomorphic adenomas of the salivary gland. ZAC1 (PLAGL1) concomitantly controls apoptosis and cell cycle arrest through separate pathways. ZAC1 also acts as a transcriptional cofactor for nuclear receptors. PLAGL2 belongs to the krueppel C2H2-type zinc-finger protein family and contains 6 C2H2-type zinc fingers. It functions as a positive regulator of transcription and localizes to the nucleus. PLAGL2 is ubiquitously expressed with particular abundance in spleen, lung and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.1) Kas K, Voz ML, Hensen K, et al. Transcriptional activation capacity of the novel PLAG family of zinc finger proteins. J. Biol. Chem. 1998; 273:23026-32. |
| Immunogen | PLAGL2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human PLAGL2. The immunogen is located within amino acids 40 - 90 of PLAGL2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| PLAGL2 antibody can be used for detection of PLAGL2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunohistochemistry at 2 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PLAGL2 |
|---|---|
| Alternative Names | PLAGL2 Antibody: ZNF900 KIAA0198 Zinc finger protein PLAGL2 Pleiomorphic adenoma-like protein 2 |
| Molecular Weight(MW) | 55 kDa |
| Tissue Specificity | At least two isoforms are known to exist. |
Application
Immunofluorescence of PLAGL2 in rat brain tissue with PLAGL2 antibody at 20 μg/ml.
Application
Immunohistochemistry of PLAGL2 in rat brain tissue with PLAGL2 antibody at 2 μg/ml.
Application
Western blot analysis of PLAGL2 in rat brain tissue lysate with PLAGL2 antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1463 - Rat Brain Tissue Lysate |
|---|---|
| Application Notes | PLAGL2 antibody can be used for detection of PLAGL2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunohistochemistry at 2 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | PLAGL2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | PLAGL2 Antibody is supplied in PBS containing 0.02% sodium azide. |
