Application
Immunohistochemistry staining of PMP22 in brain cortex tissue using PMP22 Antibody.| Product Name | PMP22 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | PMP22 is a major component of myelin expressed in the compact portion of essentially all myelinated fibers in the peripheral nervous system and is produced predominantly by Schwann cells. Studies in injured nerve suggested a role during Schwann cell growth and differentiation. PMP22 is expressed in cranial nerves but not in the mature central nervous system. Studies suggest a possible role of the PMP22 gene in the development of neoplasia in patients with neurofibromatosis and in the myelin degenerative Charcot-Marie-Tooth disease linked to chromosome 17p. |
| Immunogen | PMP22 antibody was raised against a peptide near the C-Terminus of PMP22 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| PMP22 antibody can be used in ELISA, and immunohistochemistry starting at 5 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PMP22 |
|---|---|
| Alternative Names | PMP22 CMT1E DSS GAS-3 GAS3 Growth arrest-specific 3 HMSNIA PMP-22 CMT1A HNPP Peripheral myelin protein 22 |
Application
Immunohistochemistry staining of PMP22 in brain cortex tissue using PMP22 Antibody.| Application Notes | PMP22 antibody can be used in ELISA, and immunohistochemistry starting at 5 μg/mL. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store PMP22 antibody at 4 ˚C, Avoid Freezing |
| Storage Buffer | PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide. |
