This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Kohl, B., et al. Am. J. Pathol. 176(3):1390-1399(2010) Kabzinska, D., et al. J. Appl. Genet. 51(2):203-209(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Stangler Herodez, S., et al. J. Int. Med. Res. 37(5):1626-1631(2009)
Immunogen
This PMP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from human PMP22.
Western blot analysis in human normal Uterus tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.