This gene is a member of the paraneoplastic antigen MA
(PNMA) gene family, whose protein products share homology with
retroviral Gag proteins. They are highly expressed in the brain and
also in a range of tumors associated with serious neurological
phenotypes. PMID:16407312 reports the presence of a functional -1
ribosomal frameshift signal (consisting of a heptanucleotide shift
motif followed 3' by a pseudoknot structure) in this gene, however,
the frame-shifted product has not been characterized. [provided by
RefSeq].1) Wills, N.M., et al. J. Biol. Chem. 281(11):7082-7088(2006)
Immunogen
This PNMA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-412 amino acids from the C-terminal region of human PNMA3.
Western blot analysis in Jurkat cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.