PPBP is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.1) Majumdar S.,J. Biol. Chem. 266:5785-5789(1991)
Immunogen
This PPBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-54 amino acids from the N-terminal region of human PPBP.
Western Blot at 1:1000 dilution + human spleen lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.