The PPFIA3 protein is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family, a family of transmembrane protein tyrosine phosphatases known to be important for axon guidance and mammary gland development (1). Similar to the other liprin family members, PPFIA3 can interact with ERC2, a member of the ELKS-Rab6-interacting protein-CAST family of proteins at the presynaptic termini, suggesting that these proteins may play a role in the molecular organization of presynaptic zones (2).1) Serra-Pages C, Medley QG, Tang M, et al. Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins. J. Biol. Chem. 1998; 273:15611-20.
Immunogen
PPFIA3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human PPFIA3. The immunogen is located within amino acids 1100 - 1150 of PPFIA3.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
PPFIA3 antibody can be used for detection of PPFIA3 by Western blot at 1 - 2 μg/ml.
PPFIA3 Antibody: LPNA3 KIAA0654 Liprin-alpha-3 Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3 PTPRF-interacting protein alpha-3
Molecular Weight(MW)
Predicted: 131 kDa Observed: 131 kDa
Tissue Specificity
PPFIA3 antibody is human, mouse, and rat reactive.