This gene encodes a member of the ASPP
(apoptosis-stimulating protein of p53) family of p53 interacting
proteins. The protein contains four ankyrin repeats and an SH3
domain involved in protein-protein interactions. ASPP proteins are
required for the induction of apoptosis by p53-family proteins.
They promote DNA binding and transactivation of p53-family proteins
on the promoters of proapoptotic genes. Expression of this gene is
regulated by the E2F transcription factor.1) Figl, A., et al. Mutat. Res. 702(1):8-16(2010)
Immunogen
This PPP1R13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 623-652 amino acids from the Central region of human PPP1R13B.
Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.