The protein encoded by this gene is membrane-associated
and contains five ankyrin repeats, a protein
phosphatase-1-interacting domain, and a carboxy-terminal CAAX box
domain. Synthesis of the encoded protein is inhibited by
transforming growth factor beta-1. The protein may bind to the
membrane through its CAAX box domain and may act as a signaling
molecule through interaction with protein phosphatase-1.
Alternatively spliced transcript variants encoding different
isoforms have been identified in this gene.1) Csortos, C., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 295 (3), L440-L450 (2008) :
Immunogen
This PPP1R16B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-399 amino acids from the Central region of human PPP1R16B.
Western blot analysis in HepG2 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.