The protein phosphatase-1 (PP1) catalytic subunit (PPP1CA;
MIM 176875) is regulated by targeting subunits, such as PP1R3B.
PP1R3B suppresses the rate at which PP1 dephosphorylates (i.e.,
inactivates) glycogen phosphorylase (see PYGL; MIM 232700) and
enhances the rate at which it activates glycogen synthase (see
GYS2; MIM 138571) (Doherty et al., 1995 [PubMed 7498521]).[supplied
by OMIM].1) Montori-Grau, M., et al. Biochem. J. 405(1):107-113(2007)
Immunogen
This PPP1R3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human PPP1R3B.
Western blot analysis of lysate from human skeletal muscle tissue lysate, using PPP1R3B Antibody at 1:1000 at each lane.
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.