This gene is imprinted, and located in a cluster of
imprinted genes on chromosome 7q12. This gene is transcribed in
both neuronal and multiple embryonic tissues, and it is maternally
expressed mainly in embryonic skeletal muscle tissues and
biallelically expressed in other embryonic tissues. The protein
encoded by this gene includes a PDZ domain and a sterile alpha
motif (SAM). It is a regulatory subunit of protein phosphatase I,
and controls actin cytoskeleton reorganization. Alternatively
spliced transcript variants encoding different isoforms have been
found for this gene.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This PPP1R9A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 455-484 amino acids from the Central region of human PPP1R9A.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.