Application
Immunofluorescence of PRKCDBP in human spleen tissue with PRKCDBP antibody at 20 μg/ml.| Product Name | PRKCDBP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | PRKCDBP Antibody: The protein kinase C delta (PKC-δ) binding protein (PRKCDBP), also known as cavin-3, is a member of the cavin family of proteins that are involved in caveolin formation and regulation. PRKCDBP was initially identified in a screen of cultured cell lines for proteins that were strongly induced by serum starvation. Studies indicate that PRKCDBP binds not only to PKC-δ but also to caveolin-1 and helps regulate caveolin traffic and function. Similar to other members of the cavin family, the expression of PRKCDBP was found to be down-regulated in various cancer cell lines, suggesting a possible tumor suppressor function of PRKCDBP.1) Briand N, Dugail I, and Le Lay S. Cavin proteins: New players in the caveolae field. Biochimie 2011; 93:71-7. |
| Immunogen | Rabbit polyclonal PRKCDBP antibody was raised against an 17 amino acid peptide near the center of human PRKCDBP. The immunogen is located within amino acids 150 - 200 of PRKCDBP. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFIHC-P |
| PRKCDBP antibody can be used for detection of PRKCDBP by Western blot at 1 - 2 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PRKCDBP |
|---|---|
| Alternative Names | PRKCDBP Antibody: SRBC HSRBC CAVIN3 cavin-3 SRBC Protein kinase C delta-binding protein Cavin-3 hSRBC |
| Molecular Weight(MW) | 29 kDa |
| Sequence Similarities | 2) Cat. No. 10-901 - Human Spleen Tissue Slide |
| Tissue Specificity | It is predicted to not cross-react with other members of the cavin family. |
Application
Immunofluorescence of PRKCDBP in human spleen tissue with PRKCDBP antibody at 20 μg/ml.| Positive Control | 1) Cat. No. 1288 - A20 Cell Lysate |
|---|---|
| Application Notes | PRKCDBP antibody can be used for detection of PRKCDBP by Western blot at 1 - 2 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | PRKCDBP antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | PRKCDBP Antibody is supplied in PBS containing 0.02% sodium azide. |
