PPP4C, PP4, PPH3, Protein phosphatase X, PP-X, Protein phosphatase 4, PP4C, PPP4, PPX
Product description
Protein phosphatase 4 (protein phosphatase X) is a 35kD serine/threonine phosphatase with predicted binding sites for iron and manganese. It is found in both the cytoplasm and the nucleus. The phophoprotein alpha 4 has been identified as a potential regulatory subunit. PPP4C has been shown to localize to centrosomes/spindle pole bodies and is believed to be involved in microtubule organization. It may also play a role in relaying the TNF-alpha signal to the JNK pathway. Additionally, it has been shown to associate with C-Rel, NF-Kappa B p50, and RelA. Hence, it may be involved in the activation of these key mediators of immune response and apoptosis.
Immunogen
Protein Phosphatase 4 antibody was raised against amino acids 294-307 of Protein Phosphatase 4 (Bovine).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHCWB
Protein Phosphatase 4 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.: