This intronless gene is specifically expressed in the
testis, and encodes a protein that is highly homologous to the two
subunits of phosphoribosylpyrophosphate synthetase encoded by human
X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine,
purine or pyridine bases to the corresponding ribonucleoside
monophosphates. In vitro transcription/translation and
site-directed mutagenesis studies indicate that translation of this
mRNA initiates exclusively at a non-AUG (ACG) codon. [provided by
RefSeq].1) Venter, J.C., et al. Science 291(5507):1304-1351(2001)
Immunogen
This PRPS1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the N-terminal region of human PRPS1L1.
Western blot analysis in CEM cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.