Transmembrane gamma-carboxyglutamic acid protein 1, Proline-rich gamma-carboxyglutamic acid protein 1, Proline-rich Gla protein 1, PRRG1, PRGP1, TMG1
Product description
This gene encodes a vitamin K-dependent,
gamma-carboxyglutamic acid (Gla)-containing, single-pass
transmembrane protein. This protein contains a Gla domain at the
N-terminus, preceded by a propeptide sequence required for
post-translational gamma-carboxylation of specific glutamic acid
residues by a vitamin K-dependent gamma-carboxylase. The C-terminus
is proline-rich containing PPXY and PXXP motifs found in a variety
of signaling and cytoskeletal proteins. This gene is highly
expressed in the spinal cord. Several alternatively spliced
transcript variants have been found for this gene. [provided by
RefSeq].1) Lamesch, P., et al. Genomics 89(3):307-315(2007)
Immunogen
This PRRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human PRRG1.
Western blot analysis in Hela cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.