Application
Immunohistochemistry of PRRT2 in rat brain tissue with PRRT2 antibody at 2.5 μg/ml.Application
Immunofluorescence of PRRT2 in rat brain tissue with PRRT2 antibody at 20 μg/ml.Application
Western blot analysis of PRRT2 in mouse brain tissue lysate with PRRT2 antibody at 1 μg/mL.| Product Name | PRRT2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PRRT2 Antibody: PKC, EKD1, ICCA, BFIC2, BFIS2, DSPB3, DYT10, FICCA, IFITMD1, Proline-rich transmembrane protein 2, Dispanin subfamily B member 3 |
| Product description | PRRT2 Antibody: The proline-rich transmembrane protein 2 (PRRT2) contains a proline-rich domain in its N-terminal half and is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. While little is known of the function of this protein, mutations in PRRT2 have been shown to be the causative gene of paroxysmal kinesigenic dyskinesia, which is characterized by recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary movements. Recent studies have shown that PRRT2 may also be involved in some forms of benign familial infantile epilepsy (BFIE), an autosomal dominant epilepsy syndrome.1) Wang JL, Cao L, Li XH, et al. Identification of PRRT2 as the causative gene of paroxysmal kinesigenic dyskinesias. Brain 2011; 134:3493-501. |
| Immunogen | PRRT2 antibody was raised against a 18 amino acid peptide near the center of human PRRT2 . The immunogen is located within amino acids 180 - 230 of PRRT2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| PRRT2 Antibody can be used for detection of PRRT2 by Western blot at 1 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PRRT2 |
|---|---|
| Alternative Names | PRRT2 Antibody: PKC EKD1 ICCA BFIC2 BFIS2 DSPB3 DYT10 FICCA IFITMD1 Proline-rich transmembrane protein 2 Dispanin subfamily B member 3 |
| Molecular Weight(MW) | Predicted: 43 kDa Observed: 44 kDa |
| Tissue Specificity | Multiple isoforms of PRRT2 are known to exist. |
| Entrez Gene | 112476 |
|---|---|
| Protein Accession | NP_001243371 |
Application
Immunohistochemistry of PRRT2 in rat brain tissue with PRRT2 antibody at 2.5 μg/ml.
Application
Immunofluorescence of PRRT2 in rat brain tissue with PRRT2 antibody at 20 μg/ml.
Application
Western blot analysis of PRRT2 in mouse brain tissue lysate with PRRT2 antibody at 1 μg/mL.| Positive Control | 1) Cat. No. 1403 - Mouse Brain Tissue Lysate |
|---|---|
| Application Notes | PRRT2 Antibody can be used for detection of PRRT2 by Western blot at 1 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | PRRT2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | PRRT2 Antibody is supplied in PBS containing 0.02% sodium azide. |
