Paired mesoderm homeobox protein 2, Paired-related homeobox protein 2, PRX-2, PRRX2, PMX2, PRX2
Product description
The DNA-associated protein encoded by this gene is a
member of the paired family of homeobox proteins. Expression is
localized to proliferating fetal fibroblasts and the developing
dermal layer, with downregulated expression in adult skin.
Increases in expression of this gene during fetal but not adult
wound healing suggest a possible role in mechanisms that control
mammalian dermal regeneration and prevent formation of scar
response to wounding. The expression patterns provide evidence
consistent with a role in fetal skin development and a possible
role in cellular proliferation.1) Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Immunogen
This PRRX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-250 amino acids from the C-terminal region of human PRRX2.
Western blot analysis in mouse liver tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.