This gene encodes a trypsinogen, which is a member of the
trypsin family of serine proteases. This enzyme is secreted by the
pancreas and cleaved to its active form in the small intestine. It
is active on peptide linkages involving the carboxyl group of
lysine or arginine. Mutations in this gene are associated with
hereditary pancreatitis. This gene and several other trypsinogen
genes are localized to the T cell receptor beta locus on chromosome
7.1) Joergensen, M.T., et al. Am. J. Gastroenterol. 105(8):1876-1883(2010)
Immunogen
This PRSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-107 amino acids from the Central region of human PRSS1.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.