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PRSS7 Antibody

Catalog Number:OM288979
OM288979
Discount Price
OM288979-100ul
1~2 Week
100ul
OM288979-50ul
50ul
OM288979-20ul
20ul
1~2 Week
Product Profile
Product Name PRSS7 Antibody
Antibody Type Primary Antibodies
Antigen Alias Enteropeptidase, Enterokinase, Serine protease 7, Transmembrane protease serine 15, Enteropeptidase non-catalytic heavy chain, Enteropeptidase catalytic light chain, TMPRSS15, ENTK, PRSS7
Product description This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive.1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Immunogen This PRSS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 964-994 amino acids from the C-terminal region of human PRSS7.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications FACSIHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For FACS starting dilution is: 1:10~50:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol TMPRSS15
Alternative Names Enteropeptidase
Enterokinase
Serine protease 7
Transmembrane protease serine 15
Enteropeptidase non-catalytic heavy chain
Enteropeptidase catalytic light chain
TMPRSS15
ENTK
PRSS7
Molecular Weight(MW) 113 kDa
Database Links
Entrez Gene 5651
Protein Accession P98073
Application

Application

Flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Application

immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Application

Western Blot at 1:1000 dilution + A549 whole cell lysate Lysates/proteins at 20 ug per lane.
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For FACS starting dilution is: 1:10~50:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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