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PTCH1 Antibody

Catalog Number:OM289114
OM289114
Discount Price
OM289114-100ul
1~2 Week
100ul
OM289114-50ul
50ul
OM289114-20ul
20ul
1~2 Week
Product Profile
Product Name PTCH1 Antibody
Antibody Type Primary Antibodies
Antigen Alias PTCH1, PTC, BCNS, HPE7, PTC1, PTCH, NBCCS, PTCH11
Product description PTCH1 is a member of the patched gene family. The protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. It functions as a tumor suppressor. Mutations of its gene have been associated with nevoid basal cell carcinoma syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PTCH1.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAWB
PTCH1 antibody can be used for detection of PTCH1 by ELISA at 1:312500. PTCH1 antibody can be used for detection of PTCH1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol PTCH1
Alternative Names PTCH1
PTC
BCNS
HPE7
PTC1
PTCH
NBCCS
PTCH11
Molecular Weight(MW) 37 kDa, 161 kDa, 154 kDa, 161 kDa, 144 kDa, 144 kDa, 144 kDa, 144 kDa
Database Links
Entrez Gene 5727
Protein Accession AAR21240
Application

Application

Antibody used in IHC on Human Kidney.

Application

Antibody used in WB on Human Jurkat 0.2-1 ug/ml.
Positive Control 1) Cat. No. 1205 - Jurkat Cell Lysate
Application Notes PTCH1 antibody can be used for detection of PTCH1 by ELISA at 1:312500. PTCH1 antibody can be used for detection of PTCH1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store PTCH1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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