Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA
Product description
In immature T cells the T-cell receptor beta-chain gene
(TCRB; MIM 186930) is rearranged and expressed before the TCRA (MIM
186880) chain. At this early stage, TCRB can associate with the
pre-T-cell receptor alpha chain (PTCRA). The PTCRA, together with
TCRB and the CD3 complex (see MIM 186740), minimally make up the
pre-T cell receptor (pre-TCR), which regulates early T cell
development.1) Velez, D.R., et al. Am. J. Obstet. Gynecol. 200 (2), 209 (2009) :
Immunogen
This PTCRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the C-terminal region of human PTCRA.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.