Application
Immunohistochemistry of PTER in mouse kidney tissue with PTER antibody at 2.5 μg/mL.Application
Western blot analysis of PTER in human kidney tissue lysate with PTER antibody at (A) 1 and (B) 2 μg/mL.| Product Name | PTER Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTER Antibody: HPHRP, RPR-1, Phosphotriesterase-related protein, Parathion hydrolase-related protein, hPHRP |
| Product description | PTER Antibody: PTER is a mammalian homolog to bacterial phosphotriesterases, enzymes that hydrolyze phosphotriester-containing organophosphate pesticides. It is expressed primarily in the proximal renal tubules and the gene has been localized in humans to chromosomal band 10p12 by in situ hybridization. PTER, in addition to FTO, MC4R, and NPC1 has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations. At least two isoforms of PTER are known to exist.1) Davies JA, Buchman VL, Krylova O, et al. Molecular cloning and expression pattern of rpr-1, a resiniferatoxin-binding, phosphotriesterase-related protein, expressed in rat kidney tubules. FEBS Lett.1997; 410:378-82. |
| Immunogen | PTER antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human PTER. The immunogen is located within amino acids 250 - 300 of PTER. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| PTER antibody can be used for detection of PTER by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PTER |
|---|---|
| Alternative Names | PTER Antibody: HPHRP RPR-1 Phosphotriesterase-related protein Parathion hydrolase-related protein hPHRP |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine: (88%) |
Application
Immunohistochemistry of PTER in mouse kidney tissue with PTER antibody at 2.5 μg/mL.
Application
Western blot analysis of PTER in human kidney tissue lysate with PTER antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1305 - Human Kidney Tissue Lysate |
|---|---|
| Application Notes | PTER antibody can be used for detection of PTER by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | PTER antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | PTER Antibody is supplied in PBS containing 0.02% sodium azide. |
