Application
Antibody used in IHC on Human kidney at 4.0-8.0 ug/ml.Application
Antibody used in WB on Human Jurkat 5.0 ug/ml.| Product Name | PTGS1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTGS1, COX1, COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS, PES-1 |
| Product description | Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis.Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.1) Chubb, A.J., (2006) Biochemistry 45 (3), 811-820. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PTGS1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| PTGS1 antibody can be used for detection of PTGS1 by ELISA at 1:312500. PTGS1 antibody can be used for detection of PTGS1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PTGS1 |
|---|---|
| Alternative Names | PTGS1 COX1 COX3 PCOX1 PGG/HS PGHS-1 PGHS1 PHS1 PTGHS PES-1 |
| Molecular Weight(MW) | 66 kDa, 65 kDa |
Application
Antibody used in IHC on Human kidney at 4.0-8.0 ug/ml.
Application
Antibody used in WB on Human Jurkat 5.0 ug/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | PTGS1 antibody can be used for detection of PTGS1 by ELISA at 1:312500. PTGS1 antibody can be used for detection of PTGS1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store PTGS1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
