Application
Immunohistochemistry staining of PTK2 in ductal and lobular epithelium tissue using PTK2 Antibody.| Product Name | PTK2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTK2, FADK, Fadk1, Focal adhesion kinase, FRNK, FADK 1, Focal adhesion kinase 1, FAK1, p125FAK, PPP1R71, Protein-tyrosine kinase 2, PTK2 protein tyrosine kinase 2, FAK, pp125 FA kinase, Pp125FAK |
| Product description | Focal adhesion kinase (FAK) is a non-receptor protein-tyrosine kinase that is involved in signaling pathways involved in cell motility, proliferation, and apoptosis. FAK is activated by tyrosine phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. FAK plays a potential role in oncogenic transformation resulting in increased kinase activity. |
| Immunogen | PTK2 antibody was raised against a peptide located near the internal domain of PTK2 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| PTK2 antibody can be used in immunohistochemistry starting at 1:50.: |
|
| Species Reactivity | BatBovineChickenDogGibbonGorillaHamsterHorseHumanMonkeyMouseRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PTK2 |
|---|---|
| Alternative Names | PTK2 FADK Fadk1 Focal adhesion kinase FRNK FADK 1 Focal adhesion kinase 1 FAK1 p125FAK PPP1R71 Protein-tyrosine kinase 2 PTK2 protein tyrosine kinase 2 FAK pp125 FA kinase Pp125FAK |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Application
Immunohistochemistry staining of PTK2 in ductal and lobular epithelium tissue using PTK2 Antibody.| Application Notes | PTK2 antibody can be used in immunohistochemistry starting at 1:50.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | PTK2 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
