Application
Antibody is used in Western blot to detect PTPIA2 beta in C6 cell lysate.| Product Name | PTPIA2 beta Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Receptor-type tyrosine-protein phosphatase N2, R-PTP-N2, Islet cell autoantigen-related protein, IAR, ICAAR, Phogrin, PTPRN2, KIAA0387 |
| Product description | PTPIA2beta is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus.1) Schmidli, R.S., et al., Autoimmunity 28(1):15-23 (1998). |
| Immunogen | This PTPIA2 beta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-125 amino acids from the N-terminal region of human PTPIA2 beta. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | PTPRN2 |
|---|---|
| Alternative Names | Receptor-type tyrosine-protein phosphatase N2 R-PTP-N2 Islet cell autoantigen-related protein IAR ICAAR Phogrin PTPRN2 KIAA0387 |
| Molecular Weight(MW) | 111 kDa |
Application
Antibody is used in Western blot to detect PTPIA2 beta in C6 cell lysate.| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
