Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PTPN7 Antibody (S44) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.Application
Western blot analysis of anti-PTPN7 Antibody (S44) in Jurkat cell line lysates (35ug/lane)| Product Name | PTPN7 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Tyrosine-protein phosphatase non-receptor type 7, Hematopoietic protein-tyrosine phosphatase, HEPTP, Protein-tyrosine phosphatase LC-PTP, PTPN7 |
| Product description | PTPN7 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN7 is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP has been shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which is thought to function through dephosphorylating the molecules related to MAP kinase pathway.1) Eswaran,J., Biochem. J. 395 (3), 483-491 (2006) |
| Immunogen | This PTPN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from human PTPN7. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PTPN7 |
|---|---|
| Alternative Names | Tyrosine-protein phosphatase non-receptor type 7 Hematopoietic protein-tyrosine phosphatase HEPTP Protein-tyrosine phosphatase LC-PTP PTPN7 |
| Molecular Weight(MW) | 41 kDa |
Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PTPN7 Antibody (S44) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Application
Western blot analysis of anti-PTPN7 Antibody (S44) in Jurkat cell line lysates (35ug/lane)| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
