Application
Immunohistochemistry staining of PTPRM in retina tissue using PTPRM Antibody.| Product Name | PTPRM Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | PTP mu, a R2A receptor protein tyrosine phosphatase, is composed of an extracellular segment containing a MAM domain, an immunoglobulin domain and four fibronectin type III repeats, a transmembrane segment, and two intracellular protein phosphatase domains. PTP mu has been shown to affect cell-cell aggregation, regulate cardiac myocyte Kv1.5 channel expression, and promote neurite outgrowth of retinal ganglion cells. The human PTP mu gene is localized on chromosome 18pter-q11, a region with frequent abnormalities implicated in human cancer. PTP mu may be important in responses to pathological conditions associated with the loss of cell-cell interactions in the heart. |
| Immunogen | PTPRM antibody was raised against a peptide located near the internal domain of PTPRM (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| PTPRM antibody can be used in immunohistochemistry starting at 5 μg/mL, and flow cytometry. | |
| Species Reactivity | BovineDogGibbonGorillaHumanMonkeyOrangutanRabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PTPRM |
|---|---|
| Alternative Names | PTPRM HR-PTPu PTP mu PTPRL1 RPTPM Ptpmu R-PTP-MU RPTPU |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PTPRT (56%). |
Application
Immunohistochemistry staining of PTPRM in retina tissue using PTPRM Antibody.| Application Notes | PTPRM antibody can be used in immunohistochemistry starting at 5 μg/mL, and flow cytometry. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | PTPRM antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
