Application
Immunohistochemistry staining of PTPRR in skin (formalin-fixed paraffin embedded) tissue using PTPRR Antibody.| Product Name | PTPRR Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTPRR, Ch-1 PTPase, Ch-1PTPase, EC-PTP, ECPTP, PTP-SL, NC-PTPCOM1, PC12-PTP1, PCPTP1, R-PTP-R |
| Product description | PTP r, a R7 receptor protein tyrosine phosphatase, has been shown to regulate activation and translocation of the extracellular signal-regulated kinases ERK1, ERK2, and ERK5 through a kinase interaction motif located in the N terminus of the PTP r. PTP r also downregulates ERK5 activity and effectively impedes the translocation of ERK5 to the nucleus. In mouse, two protein isoforms (PTP-SL and PTPBR7) are encoded by the same gene through developmentally regulated use of alternative promoters. In rats, two alternatively spliced isoforms that differ in their 5' untranslated regions have been documented and they show overlapping but different expression patterns in the brain. |
| Immunogen | Amino acids 249 to 265 of human PTPRR |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC |
| PTPRR antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | PTPRR |
|---|---|
| Alternative Names | PTPRR Ch-1 PTPase Ch-1PTPase EC-PTP ECPTP PTP-SL NC-PTPCOM1 PC12-PTP1 PCPTP1 R-PTP-R |
Application
Immunohistochemistry staining of PTPRR in skin (formalin-fixed paraffin embedded) tissue using PTPRR Antibody.| Application Notes | PTPRR antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 5 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | PTPRR antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
