Application
Immunohistochemistry staining of PTPRS in tonsil (formalin-fixed paraffin embedded) tissue using PTPRS Antibody.| Product Name | PTPRS Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTPRS, Bptp-1, Cryp-alpha, LAR-PTP2, PTP NE-3, PTP-varsigma, PTPSIGMA, R-PTP-S, PTP sigma, R-PTP-sigma |
| Product description | PTP sigma, n R2B/LAR receptor protein tyrosine phosphatase, is composed of immunoglobulin and fibronectin type-III repeats, a single transmembrane domain and two intracellular catalytic phosphatase domains. PTP sigma has been shown to affect neuronal development and differentiation, proliferation and/or adhesiveness of various cell types in the developing hypothalamo-pituitary axis, development of lung epithelium, and differentiation and development of the neuroendocrine system. Mice lacking PTP sigma exhibit increased neuronatal fatality, stunted growth, developmental delays and severe neurological defects including spastic movements, tremor, ataxic gait, abnormal limb flexion and defective proprioception. Increased expression of PTP sigma may be of pathogenetic significance for the defective insulin secretion in GK rat islets. Two alternatively spliced protein isoforms of PTP sigma have been documented in humans, and the shorter isoform (1502aa) has been shown to expressed strongly in the brain. |
| Immunogen | Amino acids 1350 to 1367 of human PTPRS |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC |
| PTPRS antibody can be used in ELISA starting at 1:20000 - 1:100000, Western Blot starting at 1:250 - 1:2000, and immunohistochemistry starting at 10 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | PTPRS |
|---|---|
| Alternative Names | PTPRS Bptp-1 Cryp-alpha LAR-PTP2 PTP NE-3 PTP-varsigma PTPSIGMA R-PTP-S PTP sigma R-PTP-sigma |
Application
Immunohistochemistry staining of PTPRS in tonsil (formalin-fixed paraffin embedded) tissue using PTPRS Antibody.| Application Notes | PTPRS antibody can be used in ELISA starting at 1:20000 - 1:100000, Western Blot starting at 1:250 - 1:2000, and immunohistochemistry starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | PTPRS antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
