| Product Name | Puumala Virus Glycoprotein Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Puumala virus (PUUV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) and is highly homologous to the protype hantavirus Hantaan virus (1). Like other hantaviruses, the PUUV glycoprotein is synthesized as a precursor that is posttranslationally processed into two glycoproteins G1 (Gn) and G2 (Gc). These glycoproteins interact with the PUUV nucleocapsid (NP) protein through their cytoplasmic tail, and this association has been suggested to be crucial to the binding of the ribonucleoprotein of the PUUV and the assembly of the virus particle (2).1) Vapalahti O, Kallio-Kokko H, Salonen EM, et al. Cloning and sequencing of Puumala virus Sotkamo strain S and M RNA segments: evidence for strain variation in hantaviruses and expression of the nucleocapsid protein. J. Gen. Virol. 1992; 73:829-38. |
| Immunogen | Puumala virus glycoprotein antibody was raised against a 19 amino acid peptide near the amino terminus of the Puumala virus glycoprotein. The immunogen is located within amino acids 90 - 140 of Puumala Virus Glycoprotein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| Puumala virus glycoprotein antibody can detect 10ng Puumala virus glycoprotein peptide in ELISA at 1 μg/ml. | |
| Species Reactivity | Virus |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PUUVsMgp1 |
|---|---|
| Alternative Names | Puumala Virus Glycoprotein Antibody: Envelope glycoprotein M polyprotein GP |
| Molecular Weight(MW) | N/A |
| Application Notes | Puumala virus glycoprotein antibody can detect 10ng Puumala virus glycoprotein peptide in ELISA at 1 μg/ml. |
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| Form | Liquid |
|---|---|
| Storage Instructions | Puumala virus glycoprotein antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | Puumala virus glycoprotein antibody is supplied in PBS containing 0.02% sodium azide. |
