Application
Immunohistochemistry of QSOX1 in human spleen tissue with QSOX1 antibody at 5 μg/mL.Application
Immunofluorescence of QSOX1 in human spleen tissue with QSOX1 antibody at 20 μg/ml.Application
Immunofluorescence of QSOX1 in human spleen tissue with QSOX1 antibody at 20 μg/ml.Application
Western blot analysis of QSOX1 in EL4 cell lysate with QSOX1 antibody at (A) 1 and (B) 2 μg/ml.| Product Name | QSOX1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | The QSOX1 gene, also known as Quiescin Q6, is a fusion of two ancient genes: thioredoxin and ERV1. Its expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation (1). The QSOX1 protein oxidizes sulfhydryl groups to form disulfide bonds in proteins. QSOX1 expression is induced by hypoxia (2) and appears to protect cells against oxidative stress-induced apoptosis (3).1) Coppock DL, Cina-Poppe D, and Gilleran S. The quiescin Q6 gene (QSCN6) is a fusion of two ancient gene families: thioredoxin and ERV1. Genomics 1998; 54:460-8. |
| Immunogen | QSOX1 antibody was raised against a 17 amino acid peptide near the center of human QSOX1. The immunogen is located within amino acids 360 - 410 of QSOX1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| QSOX1 antibody can be used for detection of QSOX1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | QSOX1 |
|---|---|
| Alternative Names | Quiescin Q6 sulfhydryl oxidase 1 Sulfhydryl oxidase 1 Q6 QSCN6 |
| Molecular Weight(MW) | Predicted: 65, 82 kDa Observed: 66 kDa |
| Sequence Similarities | 2) Cat. No. 10-901 - Human Spleen Tissue Slide |
| Tissue Specificity | QSOX1 antibody is human and mouse reactive. QSOX1 antibody is predicted to not cross-react with QSOX2. |
Application
Immunohistochemistry of QSOX1 in human spleen tissue with QSOX1 antibody at 5 μg/mL.
Application
Immunofluorescence of QSOX1 in human spleen tissue with QSOX1 antibody at 20 μg/ml.
Application
Immunofluorescence of QSOX1 in human spleen tissue with QSOX1 antibody at 20 μg/ml.
Application
Western blot analysis of QSOX1 in EL4 cell lysate with QSOX1 antibody at (A) 1 and (B) 2 μg/ml.| Positive Control | 1) Cat. No. 1287 - EL4 Cell Lysate |
|---|---|
| Application Notes | QSOX1 antibody can be used for detection of QSOX1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | QSOX1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | QSOX1 antibody is supplied in PBS containing 0.02% sodium azide. |
