Application
Western blot of rat cortex lysate showing specific labeling of the ~27k Rab3 protein.| Product Name | Rab 3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D (Schluter et al., 2004). These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters (Coppola et al., 2002). Specifically, Rab3’s are thought to play a key role in presynaptic vesicle trafficking and priming (Schluter et al., 2006).1) Schluter OM, Schmitz F, Jahn R, Rosenmund C, Sudhof TC (2004) A Complete Genetic Analysis of Neuronal Rab3 Function. J Neuroscience 24(29):6629-6637 |
| Immunogen | Peptide corresponding to amino acid residues from the N-terminal region of rat Rab 3, conjugated to keyhole limpet hemocyanin (KLH). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | HumanMouseRatXenopus |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Rab3a |
|---|---|
| Alternative Names | RAB3 |
| Molecular Weight(MW) | 27 |
Application
Western blot of rat cortex lysate showing specific labeling of the ~27k Rab3 protein.| Form | Liquid |
|---|---|
| Storage Instructions | Rab 3 antibody can be stored at -20˚C and is stable at -20˚C for at least 1 year. |
| Storage Buffer | 100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol. |
