Application
Western blot of rat cortex lysate showing specific immunolabeling of the ~82k rabphilin 3A.| Product Name | Rab 3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994;Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington’s disease (Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995;Foletti and Scheller, 2001).1) Foletti DL, Scheller RH (2001) Developmental regulation and specific brain distribution of phosphorabphilin. J Neurosci 21:5461-5472. |
| Immunogen | Synthetic peptide corresponding to amino acid residues from the C-terminal region of rabphilin 3A. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | BovineDogHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Rph3a |
|---|---|
| Alternative Names | Exophilin-1 |
| Molecular Weight(MW) | 82kDa |
Application
Western blot of rat cortex lysate showing specific immunolabeling of the ~82k rabphilin 3A.| Form | Liquid |
|---|---|
| Storage Instructions | Rab 3 antibody can be stored at -20˚C and is stable at -20˚C for at least 1 year. |
| Storage Buffer | 100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol. |
