Application
Antibody used in WB on Human brain at 0.2-1 ug/ml.Application
Antibody used in IHC on Human brain.| Product Name | RARB Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | RARB is a retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined.1) Uhl, G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RARB. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| RARB antibody can be used for detection of RARB by ELISA at 1:62500. RARB antibody can be used for detection of RARB by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RARB |
|---|---|
| Alternative Names | RARB HAP NR1B2 RRB2 MCOPS12 |
| Molecular Weight(MW) | 50 kDa |
Application
Antibody used in WB on Human brain at 0.2-1 ug/ml.
Application
Antibody used in IHC on Human brain.| Positive Control | 1) Cat. No. XBL-10123 - Fetal Brain Tissue Lysate |
|---|---|
| Application Notes | RARB antibody can be used for detection of RARB by ELISA at 1:62500. RARB antibody can be used for detection of RARB by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store RARB antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
