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RASAL1 Antibody

Catalog Number:OM289547
OM289547
Discount Price
OM289547-100ul
1~2 Week
100ul
OM289547-50ul
50ul
OM289547-20ul
20ul
1~2 Week
Product Profile
Product Name RASAL1 Antibody
Antibody Type Primary Antibodies
Product description The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described1) Ohta, M., et al. Gastroenterology 136(1):206-216(2009)
Immunogen This RASAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the Central region of human RASAL1.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
For WB starting dilution is: 1:1000
Species Reactivity Mouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol RASAL1
Alternative Names RasGAP-activating-like protein 1
RASAL1
RASAL
Molecular Weight(MW) 90 kDa
Database Links
Entrez Gene 8437
Protein Accession O95294
Application

Application

Western blot analysis in mouse liver tissue lysates (35ug/lane).
Application Notes For WB starting dilution is: 1:1000
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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