Application
Immunohistochemistry of RASSF10 in human lung tissue with RASSF10 antibody at 10 μg/mL.Application
Western blot analysis of RASSF10 in human lung tissue lysate with RASSF10 antibody at 1 μg/mL| Product Name | RASSF10 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RASSF10 Antibody: Ras association domain-containing protein 10 |
| Product description | RASSF10 Antibody: RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.1) Sherwood V, Manbodh R, Sheppard C, et al. RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis. Mol. Biol. Cell 2008; 19:1772-82. |
| Immunogen | RASSF10 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human RASSF10. The immunogen is located within amino acids 50 - 100 of RASSF10. |
| Modification | Acetylated |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| WB:1:500~1:2000 IHC-P:1:50~1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RASSF10 |
|---|---|
| Alternative Names | RASSF10 Antibody: Ras association domain-containing protein 10 |
| Sequence Similarities | 2) Cat. No. 10-101 - Human Lung Tissue Slide |
| Tissue Specificity | RASSF10 antibody will not cross-react with other RAS association domain-containing family members. |
| Entrez Gene | 644943 |
|---|---|
| Protein Accession | NP_001073990 |
Application
Immunohistochemistry of RASSF10 in human lung tissue with RASSF10 antibody at 10 μg/mL.
Application
Western blot analysis of RASSF10 in human lung tissue lysate with RASSF10 antibody at 1 μg/mL| Positive Control | 1) Cat. No. 1302 - Human Lung Tissue Lysate |
|---|---|
| Application Notes | WB:1:500~1:2000 IHC-P:1:50~1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | RASSF10 antibody can be stored at 4 ˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | RASSF10 Antibody is supplied in PBS containing 0.02% sodium azide. |
