Application
Western blot analysis of RASSF6 in 293 cell lysate with RASSF6 antibody at 1 μg/mL.| Product Name | RASSF6 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | RASSF6 Antibody: RASSF family proteins are tumor suppressors that are frequently downregulated during the development of human cancer. RASSF6 (Ras association (RalGDS/AF-6) domain family member 6), a member of RASSF family, acts as a Ras effector protein / tumor suppressor. RASSF6 contains one Ras-associating domain and one SARAH domain. It is involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. Defects in RASSF6 may facilitate viral NFκ-B pathway and may play a vital role in infection.1) Van der Weyden L, Adams DJ. The Ras-association domain family (RASSF) members and their role in human tumourigenesis. Biochim. Biophys. Acta 2007; 1776:58-85 |
| Immunogen | RASSF6 antibody was raised against a 14 amino acid synthetic peptide near the center of human RASSF6. The immunogen is located within amino acids 230 - 280 of RASSF6. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| RASSF6 antibody can be used for detection of RASSF6 by Western blot at 1 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RASSF6 |
|---|---|
| Alternative Names | RASSF6 Antibody: Ras association domain-containing protein 6 |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Mouse: (93%), Rat: (93%) |
| Tissue Specificity | At least four isoforms of RASSF6 are known to exist. RASSF6 antibody is predicted to not cross-react with other RASSF family members. |
Application
Western blot analysis of RASSF6 in 293 cell lysate with RASSF6 antibody at 1 μg/mL.| Positive Control | 1) Cat. No. 1210 - HEK293 Cell Lysate |
|---|---|
| Application Notes | RASSF6 antibody can be used for detection of RASSF6 by Western blot at 1 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | RASSF6 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | RASSF6 Antibody is supplied in PBS containing 0.02% sodium azide. |
