RCC1 and BTB domain-containing protein 1, Chronic lymphocytic leukemia deletion region gene 7 protein, CLL deletion region gene 7 protein, Regulator of chromosome condensation and BTB domain-containing protein 1, RCBTB1, CLLD7, E45
Product description
This gene encodes a protein with an N-terminal RCC1 domain
and a C-terminal BTB (broad complex, tramtrack and bric-a-brac)
domain. In rat, over-expression of this gene in vascular smooth
muscle cells induced cellular hypertrophy. In rat, the C-terminus
of RCBTB1 interacts with the angiotensin II receptor-1A. In humans,
this gene maps to a region of chromosome 13q that is frequently
deleted in B-cell chronic lymphocytic leukemia and other lymphoid
malignancies.1) Genuneit, J., et al. Clin. Exp. Allergy 39(12):1875-1888(2009)
Immunogen
This RCBTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-377 amino acids from the Central region of human RCBTB1.
RCC1 and BTB domain-containing protein 1 Chronic lymphocytic leukemia deletion region gene 7 protein CLL deletion region gene 7 protein Regulator of chromosome condensation and BTB domain-containing protein 1 RCBTB1 CLLD7 E45
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.